منابع مشابه
Subsystem: Ubiquinone Biosynthesis
Quinones are widely distributed in nature. They are best known as lipid-soluble components of membrane-bound electrontransport chains, but in animal cells ubiquinone is found not only in the inner mitochondrial membrane but also in the endoplasmic reticulum, Golgi apparatus, lysosomes, peroxisomes, and in the plasma membrane. This distribution suggests that ubiquinones may be involved in a numb...
متن کاملMitochondrial respiration without ubiquinone biosynthesis.
Ubiquinone (UQ), a.k.a. coenzyme Q, is a redox-active lipid that participates in several cellular processes, in particular mitochondrial electron transport. Primary UQ deficiency is a rare but severely debilitating condition. Mclk1 (a.k.a. Coq7) encodes a conserved mitochondrial enzyme that is necessary for UQ biosynthesis. We engineered conditional Mclk1 knockout models to study pathogenic eff...
متن کاملBiosynthesis of ubiquinone in the rat.
Ruegg et al. (1959) and Linn et al. (1959) have reported that rat liver contains two ubiquinones with C46 and C50 side chains (coenzymes Q, and Qlo respectively), the former predominating. Experiments in this Laboratory confirmed the presence of both these ubiquinones in our stock-colony rats and also showed the presence of traces of ubiquinones with side chains containing 40 and 35 carbon atom...
متن کاملBiosynthesis of ubiquinone in non-photosynthetic gram-negative bacteria.
1. The polyprenylphenol and quinone complements of the non-photosynthetic Gram-negative bacteria, Pseudomonas ovalis Chester, Proteus mirabilis and ;Vibrio O1' (Moraxella sp.), were investigated. 2. Ps. ovalis Chester and Prot. mirabilis were shown to contain 2-polyprenylphenols, 6-methoxy-2-polyprenylphenols, 6-methoxy-2-polyprenyl-1,4-benzoquinones, 5-demethoxyubiquinones, ubiquinones, an uni...
متن کاملPhotoregulated carotenoid biosynthesis in non-photosynthetic microorganisms.
Photoregulated carotenoid biosynthesis consists of an initiating photoactivation which bestows carotenogenic competence upon photochromogenic microorganisms. Subsequent carotenoid biosynthesis is light independent but requires microbial growth. Experimental systems have been developed for several photochromogcnic microorganisms to separate the primary photoact from the following carotenogenic r...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2001
ISSN: 0378-1097
DOI: 10.1016/s0378-1097(01)00330-5